Dynamic control of modeled tonic-clonic seizure states with closed-loop stimulation

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Dynamic control of modeled tonic-clonic seizure states with closed-loop stimulation

Seizure control using deep brain stimulation (DBS) provides an alternative therapy to patients with intractable and drug resistant epilepsy. This paper presents novel DBS stimulus protocols to disrupt seizures. Two protocols are presented: open-loop stimulation and a closed-loop feedback system utilizing measured firing rates to adjust stimulus frequency. Stimulation suppression is demonstrated...

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ژورنال

عنوان ژورنال: Frontiers in Neural Circuits

سال: 2013

ISSN: 1662-5110

DOI: 10.3389/fncir.2012.00126